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Submitted
March 17, 2016
Accepted
March 17, 2016
Published
March 10, 2016
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Abstract

It evaluates the inhibitory effect of the isolated compound with different drug targets for the anti-cancer activities. The present investigation analyses the docking score of the isolated compound with different proteins. Two types of proteins (Drug targets) were chosen against cancer namely Human Epidermal Growth Factor and Crystal structure of human placental aromatase cytochrome P450.


This result reveals that the compound 19-Hydroxy lochnericine shows hydrogen interactions with the docking energy of – 7.41 and -7.15 –8.83 kcal/mol. This reveals a significant interaction between the target proteins and the selected compound. Hence, the compound may offer therapeutic advantages in the treatment and prevention of diabetes and breast cancer.

Keywords

Isolated compound C.roseus Drug targets cytochrome P450 ADMET Docking scores

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Authors retain the copyright without restrictions for their published content in this journal. GCTL is a Sherpa Romeo Journal. 

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This is an open-access article distributed under the terms of  Creative Commons License

How to Cite
Retna, A. M., Ethalsha, P., & Lydia, J. (2016). DOCKING SCORE OF THE ISOLATED COMPOUND: 19-HYDROXY LOCHNERICINE - WITH DIFFERENT PROTEINS. Green Chemistry & Technology Letters, 2(1), 31–34. https://doi.org/10.18510/gctl.2015.216
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